Back to Team

John Crumpler

Board Member, CEO Roundtable on Cancer, Board Member, Project Data Sphere, General Partner, Hatteras Venture Partners

John co-founded Hatteras in 2000 after a successful career as a technology entrepreneur. After a decade in politics and public policy, he was founder and CEO of E-Comm, Inc., a software development and services firm specializing in remote and mobile computing. Following E-Comm’s acquisition by XcelleNet, Inc. (XNET), John ran the services division there until the company was acquired by Sterling Commerce (SE). Following the acquisition John founded Hatteras with Clay Thorp.

At Hatteras, John is responsible for the firm’s investments in healthcare and life science information technology, and overall fund operations.

With his partners at Hatteras John has helped build a seed and early stage venture capital partnership with over $600 million under management in six funds. In that time, he has served on the boards of Synthematix, a chemistry informatics company that was acquired by Symyx Technologies (SMMX); Clinverse, a financial lifecycle management technology provider to contract research organizations (CROs) and pharmaceutical companies, acquired by Bioclinica, Inc.; Bivarus, a survey-based health analytics company acquired by Press Ganey; NurseGrid, the nation’s most widely distributed nurse scheduling platform, acquired by HealthStream; and Medfusion, a leading patient engagement platform, acquired by NextGen. John currently serves on the boards of Iris Healthcare, Elligo Health Research, Wildflower Health, Jumo Health, and as an observer at SafeRide and Clinipace Worldwide. He holds an A.B. from Harvard University.


Throughout his career John has been active in government and public policy at the state and federal levels. A recipient of the Lyndhurst Prize, John served on the N. C. Economic Development Board, the state’s Clean Water Management Trust Fund board of directors, the Council for Entrepreneurial Development, and as a trustee of the University of North Carolina School of the Arts. He currently serves as a longstanding board leader at SouthLight Healthcare, a non-profit provider of substance use treatment and mental health services, on the board of the North Carolina Wildlife Federation, and on the national advisory board of Organizing for Action. He is active at White Memorial Presbyterian Church and an enthusiastic member of the OnPoint House Band that plays for worship every Sunday. He has also been a member of the Americana band, Bloomsbury, for over 30 years and plays banjo in the Southern String Band.